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2727773 
Journal Article 
Beneficial effects of L-carnitine in post-dialysis syndrome 
Casciani, CU; Caruso, U; Cra Votto, E; Corsi, M; Maccari, F 
1982 
Yes 
Current Therapeutic Research
ISSN: 0011-393X 
IPA/83/508090 
Ther 
REF 29 
116-127 
English 
IPA COPYRIGHT: ASHP Eighteen dialyzed patients received L-carnitine (I), at an oral dose of 990 mg/day for 60 days, followed by placebo for 60 days, or vice versa, for symptoms of the post-dialysis syndrome. The I blood values, assayed prior to and during the different treatments, showed a distinct increase (80%) only during I treatment. Eleven symptoms were monitored by periodical interviews prior to and during the course of the study. The 4 symptoms which exhibited changes (asthenia, cramp, intradialysis hypotension, and dyspnea after exertion) showed a ratio inversely proportional to the blood concentrations of I. When concentrations were increased, a lower incidence of the characteristic symptoms of the post-dialysis syndrome occurred.