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2735561 
Journal Article 
Food poisoning following consumption of clenbuterol-treated veal in Italy 
Brambilla, G; Loizzo, A; Fontana, L; Strozzi, M; Soprano, V; Et al 
1997 
Yes 
JAMA: Journal of the American Medical Association
ISSN: 0098-7484
EISSN: 1538-3598 
IPA/97/1134113 
VOL 278 ISS Aug 27 1997 
REF 4 
English 
IPA COPYRIGHT: ASHP Palpitations, tachycardia, nervousness, tremors, GI symptoms, and other symptoms attributed to clenbuterol contamination of veal are reported in 62 patients, ages 7-65 yr, who had consumed the contaminated meat 10 min to 3 h before the onset of symptoms. Clenbuterol was identified in all meat samples with a median of 4.5 mg/kg of edible tissue. With this level of clenbuterol, full therapeutic dosages (0.8 mcg/kg of clenbuterol) were ingested by patients who ate 10-20 g of meat. No further cases were observed during the following days. Clenbuterol has relatively nonselective beta2-agonist stimulating effects; therefore, cardiovascular signs could appear after ingestion of a normal meal. It was hypothesized that the accidental clenbuterol overdosage occurred in 1 animal, followed by clandestine slaughtering and distribution of part of the carcass.