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2738716 
Journal Article 
Topical alpha-interferon in keratoacanthomas in kidney transplant recipients 
Strumia, R; Perini, L; Fiocchi, O; Soffritti, S; Gilli, P 
1993 
1 
European Journal of Dermatology
ISSN: 1167-1122
EISSN: 1952-4013 
IPA/95/1065069 
J 
REF 10 
539-541 
IPA COPYRIGHT: ASHP The successful treatment of keratoacanthomas with topical alpha-interferon applied 4 times daily under occlusive dressing in 5 kidney transplant recipients, ages 36-58 yr, is reported. The drug was well tolerated. In the 4 cases localized on the dorsum of the hands, the detachment of the keratotic plug was observed after 20-30 days of topical therapy together with a flattening of the lesion and a slight reduction in its diameter. After another month, healing had taken place with a depressed scar. In the fifth case in which the keratoacanthoma was very small, involution occurred 2 wk later.