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HERO ID
2741794
Reference Type
Technical Report
Title
New antitumor agent--spirobromin
Author(s)
Safonova, TS; Chernov, VA; Minakova, SM; Dorokhova, MI; Mamaeva, IE; Et al
Year
1984
Report Number
IPA/85/614069
Volume
Chem
Issue
USSR
Page Numbers
375-377
Language
English
Abstract
IPA COPYRIGHT: ASHP The synthesis of 4 N,N'"-di-(beta-bromopropionyl)-N',N"-dispirotripiperazini� um salts, including spirobromin (dibrospidium chloride), is described; antitumor spectra in animal models are discussed. Efficacy of spirobromin in a wide variety of tumor models and leukemias was noted, along with low acute toxicity.
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