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HERO ID
2754111
Reference Type
Journal Article
Title
Clomiphene in pubertal-adolescent gynecomastia: a preliminary report
Author(s)
Stepanas, AV; Burnet, RB; Harding, PE; Wise, PH
Year
1977
Is Peer Reviewed?
Yes
Journal
Journal of Pediatrics
ISSN:
0022-3476
EISSN:
1097-6833
Report Number
IPA/77/274045
Volume
Pediatr
Issue
REF 10
Language
English
Abstract
IPA COPYRIGHT: ASHP Nineteen boys with gynecomastia seen in an endocrine outpatient clinic over a 30 month period were treated with clomiphene citrate (Clomid; I) in an uncontrolled trial. Treatment was initiated with I 50 mg daily and reduced to 50 mg on alternate days for maintenance when a measurable response occurred. Eighteen of the 19 (95%) patients' breast size decreased with treatment. However, it is difficult to determine the effectiveness of a drug in a disease characterized by eventual spontaneous resolution.
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