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2754229 
Journal Article 
Painful gynecomastia with ranitidine 
Tost, S; Cagnoli, M 
1982 
1 
The Lancet
ISSN: 0140-6736
EISSN: 1474-547X 
IPA/83/508040 
VOL 2 ISS Jul 17 1982 
REF 2 
English 
IPA COPYRIGHT: ASHP A 69-yr-old man with rheumatoid arthritis and a history of peptic ulcer was treated with anti-inflammatory agents (2 mg triamcinolone and 175 mg sodium diclofenac/day) and oral ranitidine (I) 150 mg/day, until he developed a tender palpable gynecomastia after 8 days. When I was stopped, the gynecomastia disappeared after 15 days, but it reappeared within 3 wk after a rechallenge with 150 mg of I twice daily. During both periods, no increase in prolactin, testosterone, and estradiol levels was recorded. The results suggest that I was the cause for the gynecomastia.