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2814558 
Technical Report 
Study on mutagenic properties of the Nakatsu River sediment 
Abe, A; Sugiyama, H; Hisamatsu, Y; Matsushita, H 
1992 
BIOSIS/93/04788 
38 
4 
366-373 
Japanese 
BIOSIS COPYRIGHT: BIOL ABS. We have reported previously the presence of mutagenicity in the extract from the sediment collected from some points of the Nakatsu river. In order to characterize mutagens in the river sediment, the extract from the Nakatsu river sediment was fractionated into 9 fractions by HPLC and tested using Salmonella typhimurium TA98, YG1021 and YG1024. The middle-high polar fractions in the extract from the sediment showed mutagenicity to YG1024 by the addition of S9 mix. Then, some aminoarenes were investigated in these fractions by NPD-GC. More polar two fractions revealed mutagenicity to TA98 without S9 mix. In these fractions some mutagenic substances were surveyed and identified by GC-MS, but unknown peaks were present. Mutagenicity, PAH concentration, amount of extract and ignition loss of the sediments from the Nakatsu river were compared with those of the Sagami river. As the result it is confirmed that the Nakatsu river is specific on mutagenic contamination.