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2817864 
Journal Article 
Simultaneous determination of urinary metabolites of workers exposed to benzene, toluene and xylene mixture with HPLC using beta-cyclodextrine 
Moon, DH; Lee, YH; Moon, CS; Kim, JH; Park, MH; Lee, CU; Paik, NW; Shim, YB 
1998 
Yes 
Bulletin of the Korean Chemical Society
ISSN: 0253-2964
EISSN: 1229-5949 
19 
12 
1306-1309 
English 
WOS:000077441000008 
The high-performance liquid Chromatographic determination of eight metabolites was evaluated with a β-cyclodextrine (β-CD) added C18 column. The urinary metabolites were hippuric acid (HA), phenol, o-, m-, p-methylhippuric acid (MHA) and o-, m-, p-cresol in untreated urine samples of factory workers exposed to benzene, toluene and xylene mixture. Eluting sequence of eight metabolites was shown to be the order of HA, o-MHA, phenol, p-MHA, m-MHA, p-cresol, m-cresol, and o-cresol. The optimum ratio of the mobile phase was selected 20/80/0.3/1.4% to ethanol/water/acetic acid/β-CD, in which was shown 2