Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
2821198
Reference Type
Journal Article
Title
Detoxification of mycotoxin patulin by the yeast Rhodosporidium paludigenum
Author(s)
Zhu, R; Feussner, K; Wu, T; Yan, F; Karlovsky, P; Zheng, X
Year
2015
Is Peer Reviewed?
Yes
Journal
Food Chemistry
ISSN:
0308-8146
EISSN:
1873-7072
Volume
179
Page Numbers
1-5
Language
English
PMID
25722132
DOI
10.1016/j.foodchem.2015.01.066
Abstract
Patulin is a mycotoxin produced by Penicillium species which often contaminates fruit and fruit-derived products. In this work the degradation of patulin by the yeast Rhodosporidium paludigenum was studied and the toxicity of the degradation product was determined. Patulin-degrading activity of R. paludigenum was inducible by patulin; it was located within yeast cells and the enzyme did not require a dissociable cofactor. Chromatographic behavior and molecular mass of the degradation product indicated that R. paludigenum transformed patulin into desoxypatulinic acid. The degradation product was significantly less toxic to Arabidopsis thaliana and human liver cells than patulin; it was not toxic to Escherichia coli at the highest concentration tested. The detoxification activity of R. paludigenum toward patulin is a promising tool for the control of patulin contamination in food and feed.
Tags
IRIS
•
Ammonia, Oral - Problem Formulation
PubMed - 3/2015
Items Screened
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity