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HERO ID
2844774
Reference Type
Journal Article
Title
To Study Serum Iron Levels in Patients of Gall Bladder Stone Disease and to Compare with Healthy Individuals
Author(s)
Prasad, PC; Gupta, S; Kaushik, N
Year
2015
Is Peer Reviewed?
Yes
Journal
Indian Journal of Surgery
ISSN:
0019-5650
EISSN:
0973-9793
Volume
77
Issue
1
Page Numbers
19-22
PMID
25829706
DOI
10.1007/s12262-012-0739-6
Web of Science Id
WOS:000351769100005
Abstract
Gallstone disease is a common gastrointestinal problem in day-to-day practice. The Old concept that a typical gallstone sufferer is fat, fertile, flatulent female of 50. This is partially true as the disease has been found in women soon after their first delivery who are thin and underweight and in males also. Conditions that favor the formation of cholesterol gallstones are super saturation of bile with cholesterol, kinetically favorable nucleation and presence of cholesterol crystals in the gall bladder long enough to agglomerate into a stone. Recent studies have defined the role of trace elements (Fe, Ca, Zn and Cu) and defective pH in the formation of gallstones. The aim of the study was to correlate iron-deficiency anemia with gallstone disease. To estimate the serum ferritin level as a diagnostic tool of iron deficiency anemia in patients with gallstone disease, this prospective study of 100 patients was conducted over a period of 24 months in the Department of General Surgery, Jaipur Golden Hospital, New Delhi, India. Serum cholesterol, iron and ferritin levels were compared in patients having gallstones and healthy individuals. A low serum iron level is a factor in bile super saturation with respect to cholesterol, leading to gallstone formation.
Keywords
Gallstone; Serum ferritin; Bile cholesterol; Anemia
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