Epidemiology of bladder cancer | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

2854722

Reference Type

Journal Article

Subtype

Review

Title

Epidemiology of bladder cancer

Author(s)

Malats, N; Real, FX

Year

2015

Is Peer Reviewed?

Yes

Journal

Hematology/Oncology Clinics of North America
ISSN: 0889-8588

Volume

Issue

Page Numbers

177-89, vii

Language

English

PMID

25836927

DOI

10.1016/j.hoc.2014.10.001

Web of Science Id

WOS:000353430000003

Abstract

Bladder cancer incidence is higher in old men, shows geographic variation, and is mostly an environmental disease. Cigarette smoking, occupational exposures, water arsenic, Schistosoma haematobium infestation, and some medications are the best established risk factors. Low-penetrance genetic factors also contribute to its origin, some through interaction with environmental factors. Bladder cancer has high prevalence and a low mortality, being largely a chronic disease. Data on environmental and genetic factors involved in the disease outcome are inconclusive.

Keywords

Bladder cancer; Urothelium; Incidence and prevalence; Smoking; Occupational risk factors; Arsenic; Genetic susceptibility