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2885973 
Journal Article 
Deep phenol peeling and fat injection: Treatment option for perioral wrinkles in a scleroderma patient 
Ramon, Y; Fodor, A; Ullmann, Y 
2005 
Yes 
Dermatologic Surgery
ISSN: 1076-0512
EISSN: 1524-4725 
31 
7 
777-779 
English 
16029706 
WOS:000230418200010 
BACKGROUND: Scleroderma is characterized by abnormal growth of connective tissue, often manifested with hard and tight skin. The viscous properties of the skin are impaired, and the main histologic changes include a thicker dermis, absence of pilosebaceous units, and a decreased space between collagen bundles. Often these patients have wound healing problems.

OBJECTIVE: The objective was to demonstrate a case of scleroderma that had deep phenol perioral peeling and fat injection into the lips. According to our bibliographic search, this is the first report in the English literature of using these modalities in scleroderma patients.

METHODS: A 64-year-old woman suffering from scleroderma for more than 20 years came for improvement of her perioral appearance. We decided to manage her deep perioral wrinkles by deep peeling using the Baker formula and concomitantly to use autologous fat injection to augment her thin lips.

RESULTS: The healing of our patient after these two interventions was uneventful, and satisfactory results have been obtained.

CONCLUSION: Based on our experience, this intervention may be suggested for patients suffering from scleroderma after a detailed explanation of the possible wound healing difficulties is provided to the patients.