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HERO ID
2917471
Reference Type
Journal Article
Title
Transplantation of Spontaneous and Induced Hepatomas in Inbred Mice
Author(s)
Andervont, HB; Dunn, TB
Year
1952
Is Peer Reviewed?
Yes
Journal
Journal of the National Cancer Institute
ISSN:
0027-8874
EISSN:
1460-2105
Report Number
NIOSH/00052872
Volume
13
Page Numbers
455-503
Abstract
Induced or spontaneous hepatomas arising in inbred mice were transplanted subcutaneously into from 1 to 4 members of their strains of origin. Of 36 hepatomas which grew in first generation hosts, 31 were propagated through 2 to 15 transplant generations, while 5 failed to grow after 1 to 6 transplant generations. Most of the successfully propagated hepatomas failed to grow in all recipients. Of 8 epatomas induced with carbon-tetrachloride (56235), none grew in new hosts.
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