Liver enzyme induction by anticonvulsant drugs, and its relationship to disturbed calcium and folic acid metabolism | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

2918243

Reference Type

Technical Report

Title

Liver enzyme induction by anticonvulsant drugs, and its relationship to disturbed calcium and folic acid metabolism

Author(s)

Latham, AN; Millbank, L; Richens, A; Rowe, DJF

Year

1973

Report Number

IPA/74/114035

Volume

Clin

Issue

REF 16

Page Numbers

1973

Language

English

Abstract

IPA COPYRIGHT: ASHP Anticonvulsant osteomalacia as a result of disturbed hepatic metabolism of vitamin D is discussed. Data was based on serum calcium and folic acid levels in 403 patients. The mean doses of the 4 most common drugs were: phenobarbital 135 mg., diphenylhydantoin (phenytoin) 290 mg., primidone 835 mg. and pheneturide (ethylphenacemide) 550 mg.