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HERO ID
2919502
Reference Type
Journal Article
Title
Metabolism of phosphoric acid triesters by rat liver homogenate
Author(s)
Sasaki, K; Suzuki, T; Takeda, M; Uchiyama, M
Year
1984
Is Peer Reviewed?
Yes
Journal
Bulletin of Environmental Contamination and Toxicology
ISSN:
0007-4861
EISSN:
1432-0800
Volume
33
Issue
3
Page Numbers
281-288
Language
English
PMID
6478075
DOI
10.1007/BF01625544
Web of Science Id
WOS:A1984TG81000006
Abstract
Very little work has been done on the metabolism of phosphates in fish, and only a few reports are available on the metabolism in mammals. In order to obtain basic data on the metabolic transformations of phosphates, the decomposition of 4 phosphates in vitro by a rat liver preparation was examined. The effects of coenzymes and inhibitors on the metabolism were investigated to elucidate the predominant enzyme reaction involved. Study materials, methods and results are discussed.
Keywords
Animals; Biotransformation; In Vitro Techniques; Liver/metabolism; Microsomes, Liver/metabolism; Mixed Function Oxygenases/metabolism; Organophosphates/metabolism; Organophosphorus Compounds/metabolism; Rats, Inbred Strains; 6145-73-9; 95UAS8YAF5
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