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Citation
Tags
HERO ID
2961506
Reference Type
Journal Article
Title
Risk of leukemia and multiple myeloma associated with exposure to benzene and other organic solvents: Evidence from the Italian multicenter case-control study
Author(s)
Seniori Costantini, A; Benvenuti, A; Vineis, P; Kriebel, D; Tumino, R; Ramazzotti, V; Rodella, S; Stagnaro, E; Crosignani, P; Amadori, D; Mirabelli, D; Sommani, L; Belletti, I; Troschel, L; Romeo, L; Miceli, G; Tozzi, GA; Mendico, I; Alberghini Maltoni, S; Miligi, L
Year
2008
Is Peer Reviewed?
Yes
Journal
American Journal of Industrial Medicine
ISSN:
0271-3586
EISSN:
1097-0274
Report Number
CIS/09/00555
Volume
51
Issue
11
Language
English
Abstract
This population-based case-control study was carried out to evaluate the association between exposure to organic solvents and risk of myeloid and lymphoid leukaemia and multiple myeloma (MM). Data concerning 586 cases of leukaemia and 1,278 population controls, as well as 263 cases of MM and 1,100 population controls were collected. Experts assessed exposure at individual level to a range of chemicals. No associations were found between exposures to any solvent and acute myeloid leukaemia. There were elevated point estimates for the associations between medium/high benzene exposure and chronic lymphatic leukaemia (odds ratio (OR) 1.8) and MM (OR 1.9). Other findings are discussed.
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