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HERO ID
2983932
Reference Type
Journal Article
Title
Emotional stress- and pain-related behaviors evoked by experimental tooth movement
Author(s)
Yozgatian, JH; Zeredo, JL; Hotokezaka, H; Koga, Y; Toda, K; Yoshida, N
Year
2008
Is Peer Reviewed?
Yes
Journal
Angle Orthodontist
ISSN:
0003-3219
Volume
78
Issue
3
Page Numbers
487-494
Language
English
PMID
18416621
DOI
10.2319/040207-165.1
Abstract
OBJECTIVE:
To investigate by behavioral methods the relationship between emotional stress and pain during experimental tooth movement in rats.
MATERIALS AND METHODS:
Sixteen male Sprague-Dawley rats (210 to 250 g) were divided into two groups. The experimental group was treated with an active Ti-Ni appliance, and the control group received a passive appliance. A force of 20 gf was delivered by the active appliance between the maxillary first and second molars for 3 days. During this period the rat's behavior was evaluated eight times by means of open-field test and resistance-to-capture test. The specific parameters of animal activity were facial grooming, rearing, and locomotor activity, movement into the center of the open field, and response to capture.
RESULTS:
Parameters related to stress and pain were higher in the group carrying active appliance, compared to the group with a passive appliance. Statistically significant differences in stress-related behavior between control and experimental groups were found 8 hours after placing the appliance and were most evident on the second day. Pain-related behavior was significantly greater in the experimental group than in the control group at 24 hours.
CONCLUSIONS:
The increase in emotional stress evoked by orthodontic tooth movement may precede the appearance of periodontal pain.
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