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3013256 
Journal Article 
Review 
Electronic Cigarettes—A Narrative Review for Clinicians 
Orellana-Barrios, MA; Payne, D; Mulkey, Z; Nugent, K 
2015 
American Journal of Medicine
ISSN: 0002-9343
EISSN: 1555-7162 
128 
674-681 
English 
Electronic cigarettes (e-cigarettes) were introduced into the US market in 2007 and have quickly become a popular source of nicotine for many patients. They are designed to simulate smoking by heating a nicotine-containing solution producing an aerosol that the user inhales. The short- and long-term effects of e-cigarette use are still unclear, but their use is increasing. Some acute effects of e-cigarettes on heart rate, blood pressure, and airway resistance are reported. Although there are some reports of improved cessation in a subset of users, there are also studies reporting decreased cessation in dual users of regular and e-cigarettes. Additionally, there is no current regulation of these devices, and this allows virtually anyone with a form of online payment to obtain them. 
Electronic cigarettes; Nicotine; Toxicity; Use patterns