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3037095 
Journal Article 
[Acute poisoning with industrial products] 
Garnier, R 
2000 
0 
La Revue du Praticien
ISSN: 0035-2640
EISSN: 2101-017X 
50 
4 
377-384 
French 
10748668 
Poisonings with industrial products represent approximately 7% of the cases reported to the poison centres. Ingestion of petroleum distillates induces irritation of the gastrointestinal tract, central nervous system depression and aspiration pneumonitis which may be severe; treatment is mainly supportive. Ethylene and diethylene glycol poisonings produce central nervous system depression, anion gap metabolic acidosis, osmolar gap and acute tubular necrosis; in severe cases, hypocalcaemia, cerebral oedema and heart failure may be observed; treatment often associates supportive measures, haemodialysis and administration of competitive inhibitors of alcohol dehydrogenase (ethanol or 4-methylpyrazole). Glycol ethers induce central nervous system depression and metabolic acidosis; in addition, ethylene glycol monobutyl ether produces haemolysis; monomethyl and monoethyl ethers are responsible for bone marrow and lymphoid organ toxicity, they adversely affect spermatogenesis and are teratogens. 
Accidents; Occupational Acute Disease Alkanes poisoning Alkenes poisoning Ethylene Glycols poisoning Female Humans Hydrocarbons; Acyclic poisoning Hydrocarbons; Aromatic poisoning Male Poisoning diagnosis Poisoning therapy Propylene Glycol poisoning Index Medicus 
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