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3038624 
Journal Article 
Solubility of Lamotrigine in Propylene Glycol plus Ethanol and Their Ternary Aqueous Mixtures 
Ghaderi, F; Barzegar-Jalali, M; Jouyban, A 
2014 
0 
Latin American Journal of Pharmacy
ISSN: 0326-2383 
33 
8 
1392-1396 
WOS:000344934100025 
The solubility of lamotrigin in binary mixtures of propylene glycol (PG) + ethanol, and ternary mixtures of PG + ethanol + water at 298.2 K was reported. The measured solubility data was mathematically represented using the Jouyban-Acree model. The accuracies of the calculated solubilities were evaluated by computing mean percentage deviation MPDs (+/- SD); the obtained MPDs were 2.9 +/- 3.4 % for binary and 10.4 +/- 6.8 % for ternary solvent mixtures. 
Cosolvency; Jouyban-Acree model; Lamotrigine; Solubility