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3041122 
Journal Article 
Effect of formulation additives on flocculation of dispersions stabilized by a non-ionic surfactant 
Zatz, JL 
1979 
Yes 
International Journal of Pharmaceutics
ISSN: 0378-5173
EISSN: 1873-3476 
IPA/82/452230 
J 
REF 5 
83-86 
English 
IPA COPYRIGHT: ASHP The effects of sodium sulfate (I) and propylene glycol (II) on flocculation of sulfamerazine (III) suspensions and mineral oil (IV) emulsions, both of which were stabilized by polysorbate 40 (Tween 40; V), are presented. Stabilities of suspensions and emulsions were assessed using the sedimentation volume and the relative cream volume, respectively. None of the emulsions inverted or cracked. Changes in both suspension and emulsion properties (flocculation) took place at |LE/5% and |LE/40% of I and II, respectively.