Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
3044703
Reference Type
Journal Article
Title
Aerobic oxidation of p-cresols to 4-hydroxy benzaldehydes catalyzed by cobaltous chloride/NHPI/salen-Cu(II) catalytic system
Author(s)
Ma, W; Zhang, Y; Li, X; Zhao, J
Year
2015
Is Peer Reviewed?
1
Journal
Research on Chemical Intermediates
ISSN:
0922-6168
EISSN:
1568-5675
Volume
41
Issue
6
Page Numbers
3855-3863
DOI
10.1007/s11164-013-1494-4
Web of Science Id
WOS:000355149900045
Abstract
Oxidation of 2-methoxy-p-cresol, p-cresol, 2-bromo-p-cresol to their corresponding 4-hydroxybenzaldehydes with atmospheric molecular oxygen as oxidant and a combination of cobaltous chloride and N-hydroxyphthalimide (NHPI) as catalyst in methanol has been investigated for the first time. The results indicated that the reaction progress was related to the substituents in the structures of the substrates: the electron-donating group methoxy favors the aerobic reaction but the electron-withdrawing group Br is detrimental to the reaction. The introduction of salen-Cu(II) complexes as the third component into the cobaltous chloride/NHPI catalytic system can considerably improve the aerobic oxidation of p-cresol and 2-brom-p-cresol to the corresponding 4-hydroxybenzaldes.
Keywords
p-cresol; 2-bromo-p-cresol; Aerobic oxidation; Cobaltous chloride; N-hydroxyphthalimide; Cu(II)-salen complexes
Tags
IRIS
•
Trimethylbenzenes (Interagency Science Discussion Draft)
Literature Search Update
Literature Search Update- Excluded
Excluded by Journal
Non Peer Reviewed
•
Trimethylbenzenes (TMB)
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity