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3055089 
Journal Article 
Review 
Gadolinium and lanthanum: a iatrogenic transmetallation? 
Brambilla, S; Valaperta, S; Graziani, G; Montanelli, A 
2008 
Yes 
Clinical Biochemistry
ISSN: 0009-9120
EISSN: 1873-2933 
41 
13 
1029-1033 
English 
18558088 
WOS:000258814500001 
An emerging skin disease inducing progressive severe dermal sclerosis and joint induration with severe movement restriction has been identified as Nephrogenic Systemic Fibrosis (NSF). In some patients NSF may rapidly progress and involve internal organs leading to fatal outcome. On May 2007 FDA issued a public health advisory concerning a possible link between NSF and exposure to gadolinium (an element of the lanthanides family) containing contrast agents used for Magnetic Resonance Angiography in advanced kidney failure (ESRD with GFR b30 mL/min) or in hemodialysis treated patients. 
Gadolinium; Lanthanum; Nephrogenic systemic fibrosis