Obstructive sleep apnoea and non-restorative sleep induced by the interface

Westhoff, M; Litterst, P

HERO ID

3174325

Reference Type

Journal Article

Year

2015

Language

English

PMID

25877806

HERO ID 3174325
In Press No
Year 2015
Title Obstructive sleep apnoea and non-restorative sleep induced by the interface
Authors Westhoff, M; Litterst, P
Journal Sleep and Breathing
Volume 19
Issue 4
Page Numbers 1317-1325
Abstract <strong>BACKGROUND: </strong>There are only few data about the influence of interfaces on restorative sleep and required CPAP/APAP levels in patients with obstructive sleep apnoea (OSA). Observations of obstructive apnoeas when using oro-nasal masks with normalisation of respiratory disturbance index (RDI) under nasal masks and of non-restorative sleep under oro-nasal masks in spite of normal RDI led to a registration of patients with such findings.<br /><br /><strong>METHODS: </strong>This study is a cohort analysis (June 1, 2006 to April 30, 2014) of patients with OSA using an oro-nasal mask and normalisation of the RDI after changing to a nasal mask and of patients complaining about a non-restorative sleep under an oro-nasal mask despite normal RDI.<br /><br /><strong>RESULTS: </strong>Sixty-five patients (BMI 32.2 ± 8.1 kg/m(2); 64.4 ± 12.8 years) with OSA (n = 54) and non-restorative sleep with normal RDI (n = 11) under oro-nasal masks were included. In the group of patients with pathologic RDI under oro-nasal masks (n = 54), switching the interface to a nasal mask normalised RDI (31.8 ± 16.3 to 6.0 ± 3.6/h [p &lt; 0.001]) and arousal index (p &lt; 0.001); slow-wave and REM sleep increased (p &lt; 0.05). In the patient group with a pathological RDI under CPAP/APAP therapy (n = 45), the pressure decreased from 9.5 ± 2.2 to 7.3 ± 2.0 cm hPa (p &lt; 0.001), and in the group with normal RDI (n = 11) from 10.1 ± 2.4 to 6.8 ± 1.2 hPa (p &lt; 0.01).<br /><br /><strong>CONCLUSION: </strong>The usage of an oro-nasal mask can result in a paradoxical induction of obstructive hypopnoeas or apnoeas. Clinicians should be aware of this phenomenon. When adapting patients to a PAP therapy, a nasal mask should be preferred even if patients report mouth breathing.
Doi 10.1007/s11325-015-1173-3
Pmid 25877806
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English