Health & Environmental Research Online (HERO)


Print Feedback Export to File
3208211 
Journal Article 
Comparison of CAIPIRINHA-VIBE, Radial-VIBE, and conventional VIBE sequences for dynamic contrast-enhanced (DCE) MRI: A validation study using a DCE-MRI phantom 
Kim, B; Lee, CK; Seo, N; Lee, SS; Kim, JK; Choi, YS; Woo, DC; Kim, IS; Nickel, D; Kim, KW 
2015 
1 
Magnetic Resonance Imaging
ISSN: 0730-725X 
English 
26747409 
OBJECTIVE: To validate radial acquisition of volumetric interpolated breath hold examination (Radial-VIBE) and the controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA-VIBE) sequences for dynamic contrast-enhanced MRI (DCE-MRI) by comparing them to conventional-VIBE sequence using a phantom.

METHODS: On a DCE-MRI phantom containing various concentrations of NiCl2 solutions, six minutes of dynamic series and T1-mapping with variable flip angle methods were acquired using conventional-VIBE, Radial-VIBE, and CAIPIRINHA-VIBE sequences on 3.0-T scanners. Signal stability and signal linearity were tested for dynamic series and the precision of R1 values were tested for T1-mapping series. The scans were repeatedly performed at two weeks and three months to test repeatability/reproducibility, assessed by within-subject coefficient of variation (WSCV).

RESULTS: Signal stability over six minutes was excellent in all three sequences. Regarding the signal linearity, CAIPIRINHA-VIBE demonstrated the highest linear correlation (r=0.963), followed by conventional-VIBE (r=0.959) and Radial-VIBE (r=0.953). Regarding the R1 precision, CAIPIRINHA-VIBE (r=0.985) was the most accurate, followed by conventional-VIBE (r=0.861) and Radial-VIBE (r=0.442). CAIPIRINHA-VIBE showed excellent repeatability/reproducibility (WSCV, 1.79-6.71%) compared with Radial-VIBE (WSCV, 2.04-67.2%) and conventional-VIBE (WSCV, 3.4-31.9%).

CONCLUSION: In terms of signal stability, signal linearity, R1 precision, and repeatability/reproducibility, CAIPIRINHA-VIBE demonstrated outstanding performance for DCE-MRI compared with Radial-VIBE and conventional-VIBE.