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HERO ID
3227477
Reference Type
Journal Article
Subtype
Review
Title
Air particulate matter and cardiovascular disease: the epidemiological, biomedical and clinical evidence
Author(s)
Du, Y; Xu, X; Chu, M; Guo, Yan; Wang, J
Year
2016
Is Peer Reviewed?
1
Journal
Journal of Thoracic Disease
ISSN:
2072-1439
EISSN:
2077-6624
Volume
8
Issue
1
Page Numbers
E8-E19
Language
English
PMID
26904258
DOI
10.3978/j.issn.2072-1439.2015.11.37
Web of Science Id
WOS:000372098000002
Abstract
Air pollution is now becoming an independent risk factor for cardiovascular morbidity and mortality. Numerous epidemiological, biomedical and clinical studies indicate that ambient particulate matter (PM) in air pollution is strongly associated with increased cardiovascular disease such as myocardial infarction (MI), cardiac arrhythmias, ischemic stroke, vascular dysfunction, hypertension and atherosclerosis. The molecular mechanisms for PM-caused cardiovascular disease include directly toxicity to cardiovascular system or indirectly injury by inducing systemic inflammation and oxidative stress in peripheral circulation. Here, we review the linking between PM exposure and the occurrence of cardiovascular disease and discussed the possible underlying mechanisms for the observed PM induced increases in cardiovascular morbidity and mortality.
Keywords
Particulate matter (PM); cardiovascular disease; morbidity; mortality
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