US EPA

3381450 

Journal Article 

Review 

Serine-threonine protein phosphatase inhibitors: Development of potential therapeutic strategies 

Mccluskey, A; Sim, ATR; Sakoff, JA 

2002 

Yes 

Journal of Medicinal Chemistry
ISSN: 0022-2623
EISSN: 1520-4804 

AMER CHEMICAL SOC 

WASHINGTON 

45 

6 

1151-1175 

English 

11881984 

10.1021/jm010066k 

WOS:000174506200001 

https://pubs.acs.org/doi/10.1021/jm010066k
Exit
 

calcineurin; calyculin A; cantharidic acid; cantharidin; cyanoginosin LR; cyclolinopeptide A; cyclosporin A; discorhabdin P; dragmacidin d; dragmacidin E; fostriecin; isopalinurin; nodularin; okadaic acid; okadamycin; palasonin; phenyl phosphate; phosphoprotein DARPP 32; phosphoprotein phosphatase; phosphoprotein phosphatase 1; phosphoprotein phosphatase 2A; phosphoprotein phosphatase 2c; phosphoprotein phosphatase 3; phosphoprotein phosphatase inhibitor; serine threonine protein phosphatase inhibitor; tacrolimus; tautomycetin; tautomycin; thyrisiferyl 23 acetate; unclassified drug; unindexed drug; amino acid sequence; apoptosis; cancer; cell cycle; cystic fibrosis; diabetes mellitus; drug activity; drug mechanism; drug targeting; enzyme activity; enzyme analysis; enzyme binding; enzyme inhibition; enzyme regulation; enzyme structure; human; immunopathology; metabolic disorder; mitosis; molecular model; nerve injury; neurologic disease; nonhuman; Parkinson disease; protein dephosphorylation; protein phosphorylation; respiratory tract disease; review; sequence homology; signal transduction; structure activity relation; Alkenes; Antibiotics, Antifungal; Antibiotics, Antineoplastic; Cantharidin; Crystallography, X-Ray; Cyclosporine; Enzyme Inhibitors; Humans; Microcystins; Models, Molecular; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatase; Pyrans; Pyrones; Spiro Compounds; Structure-Activity Relationship