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3578874 
Journal Article 
Thermodynamics of Fluconazole Solubility in Various Solvents at Different Temperatures 
Bhesaniya, K; Nandha, K; Baluja, S 
2014 
Yes 
Journal of Chemical and Engineering Data
ISSN: 0021-9568
EISSN: 1520-5134 
59 
649-652 
The solubility of Fluconazole in pure methanol, ethanol, propan-1-ol, butane-1-ol, chloroform, tetrahydrofuran, and 1,4-dioxane was measured by gravimetric method over a temperature range (298.15 to 323.15) K at atmospheric pressure. The solubility increases nonlinearly with temperature in all seven solvents. The experimental data were correlated with a modified Apelblat equation. The calculated results show good agreement with the experimental data.