The objective of this study is to compare the effect of polluted water from the El-Khashab canal (Egypt) which is a mixture of domestic and industrial effluents on the El-Saff soils, and Nile water was taken for comparison. Samples of water, soils and plants were collected from El-Khashab canal and Nile for analyses. Results showed that salinity levels, pH and heavy metals were in the permissible level in all water and soils samples. It was observed that the values of NO3- in El-Khashab canal was higher than the Nile water, which may be due to the disposal of domestic and industrial effluents in El-Khashab canal. The values of heavy metals (Fe, Mn, Co, Zn, Cu, Ni, Pb and Cd) in water and extractable soil samples were lower than the maximum permissible limits. The data revealed large different between trace elements content in different soils. The El-Khashab site showed higher contents of trace elements (Fe, Mn, Co, Zn, Cu, Ni, Pb and Cd) than the Nile site, where the average content of these elements in soils irrigated with El-Khashab canal water was 80.8, 33.8, 0.19, 22.5, 6.39, 14.6, 23.2 and 0.26 ppm, respectively. On the other hand, the irrigated soils with Nile water, contains 2.8, 8.7, 0.09, 3.44, 2.78, 0.63, 2.3 and 0.03 ppm of Fe, Mn, Co, Zn, Cu, Ni, Pb and Cd, respectively. It was found that the corn plants grown in the vicinity of El-Khashab canal, have taken up much higher Fe, Mn,Co, Zn, Cu, Ni, Pb and Cd compared to the plants grown on Nile lands. The Fe and Mn in the leaves were several times higher than in the stems. On the other hand, the decrease in Co in the leaves was most probably due to non-translocation from stems. Also, Zn, Cu and Ni uptake by corn in Nile land was lower than in El-Khashab sites. Zn uptake in the relatively polluted El-Khashab sites was higher than that of Nile land samples. Pb and Cd uptake of corn shoots in the Nile land were very far below the concentrations in corn of El-Khashab sites. Growing forage in the El-Khashab sites or using crop residues as feeds for dairy animals is dangerous to the animals and human being.