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360737 
Journal Article 
Environmental levels of cadmium, lead and mercury in brown hares and their relation to blood metabolic parameters 
Kolesarova, A; Slamecka, J; Jurcik, R; Tataruch, F; Lukac, N; Kovacik, J; Capcarova, M; Valent, M; Massanyi, P 
2008 
Journal of Environmental Science and Health, Part A: Toxic/Hazardous Substances & Environmental Engineering
ISSN: 1093-4529
EISSN: 1532-4117 
43 
646-650 
English 
The purpose of this study was to examine concentrations of selected heavy metals in the liver and kidney of brown hares (Lepus europaeus). In addition, correlations between heavy metals and biochemical parameters in blood plasma were determined. The average concentrations of heavy metals (mmol/L) ± SD were as follows: liver: Pb 0.221±0.189, Cd 0.160±0.140, Hg 0.021±0.030, kidney: Pb 0.115±0.125, Cd 1.570±1.103, Hg 0.030±0.053. The average concentrations of biochemical parameters in the blood plasma were as follows: Ca 3.16 mmol/L, P 2.19 mmol/L, Mg 1.40 mmol/L, Na 148.71 mmol/L, K 8.12 mmol/L, glucose 6.56 mmol/L, total proteins 56.49 g/L, urea 5.00 mmol/L, total lipids 1.40 g/L, bilirubin 3.97 µmol/L, cholesterol 1.53 mmol/L, aspartate aminotransferase (AST) 6.06 µkat/L and alanine aminotransferase (ALT) 1.94 µkat/L. Average levels of hormones (ng/mL) were as follows: testosterone 2.94, androstendiol 0.13, estradiol 501.59, progesterone 6.63, oxytocin 328.60. Tissue analysis showed an accumulation of lead, cadmium and mercury in the liver and kidney of brown hares. There were no significant correlations between levels of heavy metals in liver, kidney, and biochemical parameters. 
alanine aminotransferase; androstenedione; aspartate aminotransferase; bilirubin; blood chemistry; blood proteins; blood sugar; cadmium; calcium; cholesterol; contamination; estradiol; heavy metals; kidneys; lead; lipids; liver; magnesium; mercury; nitrogen; oxytocin; phosphorus; pollution; potassium; progesterone; sodium; testosterone; Lepus europaeus; Lepus; Leporidae; Lagomorpha; mammals; vertebrates; Chordata; animals; small mammals; eukaryotes; blood glucose; blood plasma proteins; blood serum proteins; environmental pollution; glucose in blood; glutamate pyruvate transaminase; glutamic pyruvic transaminase; GOT; GPT; lipins; ocytocin; oestradiol; Pollution and Degradation (PP600); Physiology and Biochemistry (Wild Animals) (YY400) (New March 2000); Toxicology and Poisoning (Wild Animals) (YY900) (New March 2000)