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Citation
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HERO ID
3684266
Reference Type
Journal Article
Title
New submonomers for poly N-substituted glycines (peptoids)
Author(s)
Uno, T; Beausoleil, E; Goldsmith, RA; Levine, BH; Zuckermann, RN
Year
1999
Is Peer Reviewed?
1
Journal
Tetrahedron Letters
ISSN:
0040-4039
EISSN:
1873-3581
Publisher
Elsevier
Book Title
Tetrahedron Letters
Volume
40
Issue
8
Page Numbers
1475-1478
DOI
10.1016/S0040-4039(98)02696-3
Web of Science Id
WOS:000078513400014
URL
https://linkinghub.elsevier.com/retrieve/pii/S0040403998026963
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Abstract
Abstract: Five protected submonomers for peptoid synthesis were prepared, including N(in)-BOC-tryptamine, O-t-butyl tyramine, PMC-guanidino-propylamine, 6-amino-6-deoxy-D-galactopyranose diacetonide, and 5-amino-2,2-dimethyl-1,3-dioxane. The first three mimic natural aminoacid sidechains i.e, tryptophan, tyrosine, and arginine, while the last two provide hydrophilic sidechains. These submonomers were successfully used for preparation of oligo-peptoids by the submonomer synthesis method. (C) 1999 Elsevier Science Ltd. All rights reserved. ds: Chemistry cument Delivery No.: 165GU e field[29]: 1,4-Dioxane
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OPPT REs
•
OPPT_1,4-Dioxane_D. Exposure
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