Synthesis, Characterization and Biological Studies of a Mannich Base N-[Phenyl(pyrrolidin-1-yl)methyl]acetamide and Its VO(IV), Mn(II) and Fe(II) Complexes | Health & Environmental Research Online (HERO)

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Tags

HERO ID

3698086

Reference Type

Journal Article

Title

Synthesis, Characterization and Biological Studies of a Mannich Base N-[Phenyl(pyrrolidin-1-yl)methyl]acetamide and Its VO(IV), Mn(II) and Fe(II) Complexes

Author(s)

Muruganandam, L; Kumar, KK; Balasubramanian, K

Year

2013

Is Peer Reviewed?

Yes

Journal

Asian Journal of Chemistry
ISSN: 0970-7077
EISSN: 0975-427X

Volume

Issue

Page Numbers

2189-2191

Web of Science Id

WOS:000312621500097

Abstract

N-[Phenyl(pyrrolidin-1-yl]methyl]acetamide was synthesized using Mannich reaction. The complexes of oxovanadium(IV), manganese(II) and iron(II) with this Mannich base were prepared and characterized by elemental analysis and spectral measurements. The spectral data reveal that the ligand acts as bidentate coordination to the metal ion through the CNC nitrogen and carbonyl oxygen atoms. Based on the UV spectral and magnetic moment data, octahedral geometry is assigned for all the complexes. The antimicrobial screening shows that the complexes are more active than the ligand.

Keywords

VO(TV); Mn(II); Fe(II); Complexes; Mannich base; Disc diffusion; Octahedral geometry; Biological study