Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
3722733
Reference Type
Journal Article
Title
Mn-Zn Ferrite and Photosensitizer Co-loaded Cancer Theragnostic Agent for Magnetic Resonance Imaging and Photodynamic Therapy
Author(s)
Lai, SyuM; Yang, MDa; Tung, MJue; Lai, PS
Year
2012
Page Numbers
226-229
Web of Science Id
WOS:000391249300058
Abstract
In this report, a multifunctional cancer diagnostic system based on manganese-zinc ferrite (MZF) and chlorin e6 (Ce6) co-loaded nanoclusters were demonstrated for magnetic resonance imaging (MRI) and photodynamic therapy (PDT). The results showed that the MZF and Ce6 co-loaded nanoclusters with particle size around 100 nm exhibited almost non-toxic to the KB cells under 200 mu g Fe/ml and had better T2 relaxivity and darker T2-weighted MR images comparing to the commercial Resovist. Thus, this system may have highly potential diagnostic abilities for in nasopharyngeal cancer or other cancers.
Keywords
Manganese zinc ferrite; nano-clusters; magnetic resonance imaging; photodynamic therapy; theragonostic agents
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity