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3829606 
Journal Article 
A recyclable copper catalysis in modified Friedlander quinoline synthesis 
Cho, CSik; Ren, WenXiu; Yoon, NamSik 
2009 
Yes 
Journal of Molecular Catalysis A: Chemical
ISSN: 1381-1169 
299 
1-2 
117-120 
WOS:000263196400017 
2-Aminobenzyl alcohol reacts with ketones in dioxane at 100 degrees C in the presence of a catalytic amount of a copper catalyst along with KOH and MS 4A under O(2) atmosphere to afford the corresponding quinolines in good yields. The catalytic system could be recovered and reused 10 times without any loss of catalytic activity. A similar catalytic System using copper catalyst/PEG-2000 is also effective for this coupling and cyclization with a similar catalytic potential. 2-Aminobenzyl alcohol is also coupled and cyclized with secondary alcohols Under the CuCl(2)/MS 4A catalytic system to give quinolines in moderate to good yields. (c) 2008 Elsevier B.V. All rights reserved. 
2-Aminobenzyl alcohol; Recyclable copper catalyst; MS 4A; Quinolines; Ketones; Cyclization