Health & Environmental Research Online (HERO)


Print Feedback Export to File
3830240 
Journal Article 
Synthesis and antimicrobial screening of 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c]benzopyran-4-one and 4H-3-methyl-2-phenyl furo[3,2-c]benzopyran-4-one 
Mulwad, VV; Hegde, AS 
2009 
Indian Journal of Chemistry. Section B
ISSN: 0376-4699
EISSN: 0975-0983 
48 
128-133 
English 
3-Acety-4-hydroxy-2H[1]benzopyran-2-one 2a-d has been treated with bromodeoxybenzoin in NaOH, THF:HMPA to give 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c] benzopyran-4-one 3a-d. This on treatment with aqueous HC1 in presence of dioxane gives 4H-3-methyl-2-phenyl furo[3,2-c] benzopyran-4-one 4a-d through acid catalysed 1,2-elimination. All compounds have been screened for antimicrobial activity. They do not show significant activity. 
Bromodeoxybenzoin; dioxane; furobenzopyran; herbicidal; antimicrobial activity