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HERO ID
3830640
Reference Type
Journal Article
Title
Microwave Assisted Synthesis of Coumarin[3,4-c] Six-membered Heterocyclic Derivatives via 1,4-Michael Addition Reaction
Author(s)
Yan, S; Lin, Jun
Year
2010
Is Peer Reviewed?
1
Journal
Youji Huaxue / Chinese Journal of Organic Chemistry
ISSN:
0253-2786
Volume
30
Issue
3
Page Numbers
465-468
Web of Science Id
WOS:000276472100023
Abstract
A series of coumarin[3,4-c] six-membered heterocyclic derivatives were synthesized via 1,4-Michael addition, condensation and aromatization of coumarin and heterocyclic ketene aminals catalyzed by potassium hexamethyldisilazane (KHMDS) in dioxane under microwave irradiation. The reactions were completed in 20 min with 60%similar to 87% yields, easy work-up and short reaction time.
Keywords
coumarin; microwave; heterocyclic ketene aminal
Tags
OPPT REs
•
OPPT_1,4-Dioxane_D. Exposure
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