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HERO ID
3831243
Reference Type
Journal Article
Title
A cooperative beads-on-a-string approach to exceptionally stable DNA triplexes
Author(s)
Zheng, Y; Long, H; Schatz, GC; Lewis, FD
Year
2006
Is Peer Reviewed?
Yes
Journal
Chemical Communications
ISSN:
1359-7345
EISSN:
1364-548X
Issue
36
Page Numbers
3830-3832
Language
English
PMID
16969472
DOI
10.1039/b607941e
Web of Science Id
WOS:000240488100020
Abstract
A poly(dT) oligomer can serve as the string on which synthetic hairpins possessing poly(dA) and poly(dT) arms connected by a hydrophobic perylene diimide linker are assembled like beads on a string. The synthetic hairpins form head-to-head dimers and trimers, respectively, in the absence of the poly(dT) string and in the presence of a string with inverted polarity at mid-strand. However, they assemble in cooperative head-to-tail fashion on normal poly(dT) oligomers.
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