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3838034 
Journal Article 
A CONVENIENT AND NEW ONE-STEP SYNTHESIS OF 1H-IMIDAZOLE-2-CARBOXAMIDES 
Singh, B 
1992 
Yes 
Heterocycles
ISSN: 0385-5414 
34 
12 
2373-2378 
WOS:A1992KE05400018 
1,2-Diketone monophenylhydrazones (2) reacted with aminomalonamide in 1-methyl-2-pyrrolidinone to provide 1-H-imidazole-2-carboxamides (4). The condensation of 1-(4-pyridinyl)-2-propanone with phenyldiazonium chloride gave 1-phenylhydrazono-1-(4-pyridinyl)-2-propanone (2a). 4-Methyl-5-(4-pyridinyl)-1H-imidazole-2-carboxamide (4a) was converted to the corresponding nitrile (5a) by the action of phosphorous oxychloride.