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4078225 
Journal Article 
Review 
Alcohol metabolism 
Cederbaum, AI 
2012 
0 
Clinics in Liver Disease
ISSN: 1089-3261 
16 
4 
667-685 
English 
23101976 
WOS:000312619400003 
is also published as 10922554 Alcohol Metabolism
This article describes the pathways and factors that modulate blood alcohol levels and metabolism and describes how the body disposes of alcohol. The various factors that play a role in the distribution of alcohol in the body, influence the absorption of alcohol, and contribute to first-pass metabolism of alcohol are described. Most alcohol is oxidized in the liver, and general principles and overall mechanisms for alcohol oxidation are summarized. The kinetics of alcohol elimination in-vivo and the various genetic and environmental factors that can modify the rate of alcohol metabolism are discussed.