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4090398 
Technical Report 
Method for Modulating Microbial Quorum Sensing 
Handelsman, JE; Borlee, BR 
2005 
NTIS/03180227 
GRA and I 
GRA and I 
The present invention provides compositions and methods for modulating bacterial quorum sensing using antagonist or agonist compounds. Further, the present invention provides methods of treating or preventing microbial damages and diseases, in particular for diseases where there is an advantage in inhibiting quorum sensing regulated phenotypes of pathogens.