Health & Environmental Research Online (HERO)


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4106866 
Journal Article 
Augmented TGFβ receptor signaling induces apoptosis of pancreatic carcinoma cells 
Li, C; Zhao, Z; Zhou, Z; Liu, R 
2015 
1 
Tumor Biology
ISSN: 1010-4283
EISSN: 1423-0380 
36 
4 
2815-2819 
English 
25476855 
WOS:000352885900069 
has retraction 4098513 Retraction Note to multiple articles in Tumor Biology
Pancreatic ductal adenocarcinoma (PDAC) is an extremely malignant tumor in humans. Thus, understanding the tumorigenesis of PDAC appears to help develop efficient therapy. Here, we show that activated TGFβ receptor signaling induces apoptosis of pancreatic carcinoma cells in vitro and in vivo, suggesting that activation of TGFβ receptor signaling may prevent development of PDAC.