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4115428 
Journal Article 
Stability of granisetron hydrochloride with dexamethasone sodium phosphate for 14 days 
Chin, A; Suk, Y; Moon, K; Chung, KC; Gill, MA 
1996 
Yes 
American Journal of Health-System Pharmacy
ISSN: 1079-2082
EISSN: 1535-2900 
IPA/96/1101399 
53 
10 
1174-1176 
English 
WOS:A1996UK77900015 
IPA COPYRIGHT: ASHP The stability and compatibility of 10 and 40 mcg/ml of granisetron hydrochloride (Kytril) and 80 and 600 mcg/ml of dexamethasone sodium phosphate (dexamethasone 21-disodium phosphate) mixed together in 5% dextrose and in 0.9% sodium chloride injection in polyvinyl chloride (PVC) were studied. Means of at least 90% of the initial concentrations of dexamethasone phosphate and granisetron remained after the samples had been stored for up to 14 days at 23 or 4DGC in either 5% dextrose or 0.9% sodium chloride injections. Visual inspection at the time of assay showed no color change, change in clarity, or precipitation. It was concluded that granisetron hydrochloride in the presence of dexamethasone sodium phosphate was stable for up to 14 days at 23-25DGC or 4DGC.