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4118606 
Journal Article 
Determination of Galangin in Commercial Extracts of Alpinia officinarum by RP-HPLC-DAD 
Verza, SG; Pavei, C; Borre, GL; Silva, AnaPC; Ortega, GG; Mayorga, P 
2011 
0 
Latin American Journal of Pharmacy
ISSN: 0326-2383 
30 
3 
576-579 
WOS:000293057100027 
Alpinia officinarum has been used by long time in the traditional medicine and several commercial extracts containing it are available on the market. In this paper a reversed phase high performance liquid chromatography-diode array detection (RP-HPLC-DAD) method for Alpinia officinarum preparations was proposed using galangin as a marker. The quantification was undertaken by a combination of RP-HPLC-DAD. The LC system employed a Gemini Phenomenex RP-18 column with phosphoric acid, tetrahydrofuran and acetonitrile as mobile phase and detection at 267 nm. The method validation was throughout satisfactory. The determination coefficient was r(2) = 0.998 with LOD 0.48 mu g mL(-1) and LOQ 159 mu g mL(-1). The results of precision (RSD < 2.82) and accuracy (99.9 %, 100.4 %, 102.2 %) with RSD less than 2.7 %, were satisfactory. The analytical method was applied to commercial extracts, and was suitable to provide qualitative and quantitative information for the quality control to commercial preparations. 
Alpinia officinarum; Galangin; RP-HPLC-DAD