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4284425 
Journal Article 
Copper-catalyzed regioselective allylic oxidation of olefins via C-H activation 
Zhu, N; Qian, Bo; Xiong, H; Bao, H 
2017 
1 
Tetrahedron Letters
ISSN: 0040-4039
EISSN: 1873-3581 
58 
43 
4125-4128 
WOS:000413386300024 
A regioselective oxidation of allylic C-H bond to C-O bond catalyzed by copper (I) was developed with diacyl peroxides as oxidants. The oxidation of allylic C-H bond was accomplished with good yield and regioselectivity under mild reaction conditions. This method has a broad substrate scope including cyclic olefins, terminal and internal acyclic olefins and allyl benzene compounds. The reaction proceeds by a radical mechanism as suggested by spin trapping experiments. (C) 2017 Elsevier Ltd. All rights reserved. 
Allylic oxidation; Olefin; Regioselective; Diacyl peroxides; Copper catalysis; Allylic radical