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4320432 
Journal Article 
NATURAL ANTIOXIDANTS OF HUMIC AND FULVIC ACIDS AGAINST OXIDATIVE STRESS INDUCED BY HYDROGEN PEROXIDE: IN-VIVO STUDIES 
Afify, AbdElMMR; Konswa, OK 
2017 
Fresenius Environmental Bulletin
ISSN: 1018-4619
EISSN: 1610-2304 
26 
10 
5841-5848 
Fulvic acid (FA) and humic acid (HA) are formed through the degradation of organic substances by chemical and biological process. Fulvic acids and humic acid has been found to possess the highest activity as antioxidant scavenging. Treatments of humic acid at different concentrations with 10,50,100 and 150 mg/Kg showed a significant differences in kidney function and liver function. The results exhibited a significant concentration-dependent manner of free radical scavenging activity as well as significant reduction of MDA level. The lowest lipid peroxidation has been reported with 150 mg/kg B.W. Humic acid and fulvic acid showed a significant decrease in the enzymes activity of glutathione peroxidase and superoxide dismutase indicating their direct protective effects against induced hydrogen peroxide. The antioxidant properties of the FA and HA partially support the health beneficial to enhance certain aspects of plant growth or mixed with fertilizers/chemicals. 
Fulvic acid; Humic acids; In vivo antioxidant scavenging capacity; kidney function; liver function