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4487374 
Journal Article 
Examination of an Internal Standard Substance for the Quantitative Analysis of Sarin Using super(31)P-NMR 
Miyata, Y; Ando, H 
2001 
Yes 
Journal of Health Science
ISSN: 1344-9702
EISSN: 1347-5207 
47 
1 (2001) 
75-77 
WOS:000166839000014 
The toxic solution used at the Tokyo Subway Sarin Incident was purified by vacuum distillation. We were thus able to obtain sarin with high purity. We conducted a quantitative analysis of sarin using super(31)P-NMR spectrometry. High-purity sarin was examined by trimethyl phosphate as an internal standard. In comparison with super(1)H nondecoupling, the relative intensity between sarin and the internal standard did not change in super(1)H decoupling. Trimethyl phosphate is a good internal standard substance. A super(31)P-NMR chemical shift of trimethyl phosphate is separate from those of sarin and related compounds. Trimethyl phosphate has one phosphorus atom in the molecule, as does sarin. Since it is advantageous in the conversion of quantitative value, the molecular weight of trimethyl phosphate (m.w. 140.08) is close to that of sarin (m.w. 140.09). By using trimethyl phosphate as an internal standard, it is possible to conduct a quantitative analysis of sarin through super(1)H decoupled super(31)P-NMR spectrometry. 
Chemical warfare agents; Sarin; N.M.R.; Standards