Health & Environmental Research Online (HERO)


Print Feedback Export to File
4681858 
Book/Book Chapter 
Cytokine response of mice to heavy metal intoxication and Ascaris suum infection 
Dvorožňáková, E; Jalčová, M 
2013 
Medimond 
Bologna, Italy 
XI European Multicolloquium of Parasitology (EMOP 11) 
25-27 
English 
WOS:000321895000006 
Mice were chronically intoxicated with lead (Pb), cadmium (Cd) or mercury (Hg) and subsequently infected with Ascaris suum. Pb and Hg modulated murine immune response in Th2 type, that dominated also after subsequent infection and caused more intensive development of parasite infection in mice intoxicated with Pb. Low numbers of parasite larvae in mice intoxicated with Hg were not associated with an effective immune response but with a cachectic status of animals. Cd stimulated IFN-gamma production and Th1 immune response, which induced reduction and destruction of larvae in the liver of intoxicated mice. 
Cozma, V 
9788875876692 
11th European Multicolloquium of Parasitology (EMOP) 
Cluj Napoca, Romania 
July 25-29, 2012