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4702878 
Journal Article 
SYNTHESIS Best Paper Award 2016: Enantioselective Vicinal Diacetoxylation of Alkenes under Chiral Iodine(III) Catalysis 
Muniz, K 
2017 
1 
Synthesis
ISSN: 0039-7881
EISSN: 1437-210X 
GEORG THIEME VERLAG KG 
STUTTGART 
49 
11 
A93-A95 
WOS:000404003000002 
Background. Thieme Chemistry and the Editors of SYNTHESIS and SYNLETT present the 'SYNTHESIS/SYNLETT Best Paper Awards'. These annual awards honor the authors of the best original research papers in each of the journals, considering their immediate impact on the field of chemical synthesis. Kilian Muniz and Thorsten H. Woste from the Catalan Institution for Research and Advanced Studies and The Barcelona Institute of Science and Technology (Spain) are the recipients of the SYNTHESIS Best Paper Award 2016. The authors are recognized for their work on the enantioselective vicinal diacetoxylation of alkenes under chiral iodine(III) catalysis. Paul Knochel, Editor-in-Chief of SYNTHESIS, commented: "The development of new catalytic asymmetric synthesis of chiral molecules is especially important for pharmaceutical and fine chemistry in general. Kilian Muniz and Thorsten Woste have reported a very mild method for converting styrene and a range of related functionalized styrene derivatives into the corresponding vicinal diacetoxy derivatives with excellent enantioselectivities (up to 96% ee). The reactions proceed via a hypervalent iodine(III) catalytic species generated in situ. This enantioselective method is not only important by itself, but the results reported in this SYNTHESIS Best Paper 2016 will be very instructive for the future development of similar hypervalent iodine catalyzed difunctionalizations of alkenes. This work will be of interest both for synthetic applications as well as for the comprehension of iodine(I/III)-catalyzed enantioselective addition."SYNFORM talked to Kilian Muniz who was happy to share some background information regarding the prize-winning paper as well as current research activities ongoing in his group.