Health & Environmental Research Online (HERO)


Print Feedback Export to File
4715082 
Journal Article 
Epoxide Hydrolases and their Application in Organic Synthesis 
Kotik, M; Archelas, A; Wohlgemuth, R 
2012 
Yes 
Current Organic Chemistry
ISSN: 1385-2728
EISSN: 1875-5348 
16 
451-482 
The number of synthetic applications of epoxide hydrolases in organic chemistry has reached a remarkable level. This has been due to a tremendous amount of work dedicated to the discovery of novel epoxide hydrolases from various biological sources, understanding the structure and function of these widespread enzymes and last but not least, the stabilization of these biocatalysts by various means for production purposes. 
Oxiranes; Enantioselectivity; Enantioconvergence; Kinetic Resolution; Desymmetrization; Asymmetric Synthesis; Biotransformation; Biocatalysis; Vicinal Diol; Chiral Synthon; Building Block