Lithium triflate (LiOTf) catalyzed efficient and chemoselective tetrahydropyranylation of alcohols and phenols under mild and neutral reaction conditions | Health & Environmental Research Online (HERO)

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HERO ID

4724119

Reference Type

Journal Article

Title

Lithium triflate (LiOTf) catalyzed efficient and chemoselective tetrahydropyranylation of alcohols and phenols under mild and neutral reaction conditions

Author(s)

Karimi, B; Maleki, W

Year

2002

Is Peer Reviewed?

Journal

Tetrahedron Letters
ISSN: 0040-4039
EISSN: 1873-3581

Volume

Issue

Page Numbers

5353-5355

DOI

10.1016/S0040-4039(02)00892-4

Web of Science Id

WOS:000176727200034

URL

http://www.sciencedirect.com/science/article/pii/S0040403902008924
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Abstract

Different types of alcohols and phenols were effectively converted to the corresponding THP ethers in the presence of DHP and a catalytic amount Of lithium trifluoromethanesulfonate (LiOTf) in refluxing 1,2-dichloroethane under essentially neutral reaction conditions. The method also shoals good chemoselectivity For mono-tetrahydropyranylation of symmetrical diols. (C) 2002 Elsevier Science Ltd. All rights reserved.